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Nonlinear accumulation of propranolol enantiomers.

The accumulation of (+)- and (-)-propranolol was investigated in nine subjects who received 160 mg of racemic propranolol as a single dose and then once daily for 7 days. The serum concentrations of propranolol enantiomers were measured by h.p.l.c. using a novel chiral stationary phase allowing dire...

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Autors principals: Lalonde, R L, Bottorff, M B, Straka, R J, Tenero, D M, Pieper, J A, Wainer, I W
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386507/
https://ncbi.nlm.nih.gov/pubmed/3203053
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