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Lamin A/C Binding Protein LAP2α Is Required for Nuclear Anchorage of Retinoblastoma Protein

The phosphorylation-dependent anchorage of retinoblastoma protein Rb in the nucleus is essential for its function. We show that its pocket C domain is both necessary and sufficient for nuclear anchorage by transiently expressing green fluorescent protein (GFP) chimeras of Rb fragments in tissue cult...

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Udgivet i:Mol Biol Cell
Principais autores: Markiewicz, Ewa, Dechat, Thomas, Foisner, Roland, Quinlan, Roy. A, Hutchison, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-07-0450
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