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Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine.

1. The effects of age on the pharmacology of nifedipine were investigated in 11 young and six elderly normotensive volunteers. 2. Following 2.5 mg of nifedipine i.v. the plasma clearance of nifedipine was 348 +/- 83 (s.d.) ml min-1 in the elderly compared with 519 +/- 125 ml min-1 in the young (P le...

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Bibliografiske detaljer
Main Authors: Robertson, D R, Waller, D G, Renwick, A G, George, C F
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386353/
https://ncbi.nlm.nih.gov/pubmed/3358895
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