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Entamoeba histolytica Expressing a Dominant Negative N-Truncated Light Subunit of Its Gal-Lectin Are Less Virulent

The 260-kDa heterodimeric Gal/GalNAc-specific Lectin (Gal-lectin) of Entamoeba histolytica dissociates under reducing conditions into a heavy (hgl, 170 kDa) and a light subunit (lgl, 35 kDa). We have previously shown that inhibition of expression of the 35-kDa subunit by antisense RNA causes a decre...

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Udgivet i:Mol Biol Cell
Principais autores: Katz, Uriel, Ankri, Serge, Stolarsky, Tamara, Nuchamowitz, Yael, Mirelman, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-06-0344
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