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Peroxisome Senescence in Human Fibroblasts

The molecular mechanisms of peroxisome biogenesis have begun to emerge; in contrast, relatively little is known about how the organelle functions as cells age. In this report, we characterize age-related changes in peroxisomes of human cells. We show that aging compromises peroxisomal targeting sign...

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Detalhes bibliográficos
Main Authors: Legakis, Julie E., Koepke, Jay I., Jedeszko, Chris, Barlaskar, Ferdous, Terlecky, Laura J., Edwards, Holly J., Walton, Paul A., Terlecky, Stanley R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC138630/
https://ncbi.nlm.nih.gov/pubmed/12475949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-06-0322
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