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Characterisation of theophylline metabolism in human liver microsomes.

1. A radiometric high performance liquid chromatographic method is described for the assay of theophylline metabolism in vitro by the microsomal fraction of human liver. 2. Formation of the three metabolites of theophylline (3-methylxanthine, 1-methylxanthine and 1,3-dimethyluric acid) were linear w...

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Detalhes bibliográficos
Main Authors: Robson, R A, Matthews, A P, Miners, J O, McManus, M E, Meyer, U A, Hall, P M, Birkett, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386249/
https://ncbi.nlm.nih.gov/pubmed/3663445
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