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Reduction of metformin renal tubular secretion by cimetidine in man.

To determine whether cimetidine altered the renal handling of metformin, seven subjects took 0.25 g metformin daily with and without cimetidine 0.4 g twice daily. Blood and urine samples were collected and assayed for metformin, cimetidine and creatinine by h.p.l.c. Cimetidine significantly increase...

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Main Authors: Somogyi, A, Stockley, C, Keal, J, Rolan, P, Bochner, F
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386190/
https://ncbi.nlm.nih.gov/pubmed/3593625
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