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Ghrelin receptor mutations — too little height and too much hunger

The ghrelin receptor is known from in vitro studies to signal in the absence of the hormone ghrelin at almost 50% of its maximal capacity. But, as for many other 7-transmembrane receptors, the in vivo importance of this ligand-independent signaling has remained unclear. In this issue of the JCI, Pan...

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Autors principals: Holst, Birgitte, Schwartz, Thue W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386123/
https://ncbi.nlm.nih.gov/pubmed/16511600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27999
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