Characterization of the reversible phosphorylation and activation of ERK8

ERK8 (extracellular-signal-regulated protein kinase 8) expressed in Escherichia coli or insect cells was catalytically active and phosphorylated at both residues of the Thr-Glu-Tyr motif. Dephosphorylation of the threonine residue by PP2A (protein serine/threonine phosphatase 2A) decreased ERK8 acti...

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Main Authors: Klevernic, Iva V., Stafford, Margaret J., Morrice, Nicholas, Peggie, Mark, Morton, Simon, Cohen, Philip
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386035/
https://ncbi.nlm.nih.gov/pubmed/16336213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051288
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