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Biliverdin reductase: A major physiologic cytoprotectant

Bilirubin, an abundant pigment that causes jaundice, has long lacked any clear physiologic role. It arises from enzymatic reduction by biliverdin reductase of biliverdin, a product of heme oxygenase activity. Bilirubin is a potent antioxidant that we show can protect cells from a 10,000-fold excess...

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Autors principals: Barañano, David E., Rao, Mahil, Ferris, Christopher D., Snyder, Solomon H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC138570/
https://ncbi.nlm.nih.gov/pubmed/12456881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252626999
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