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Biliverdin reductase: A major physiologic cytoprotectant
Bilirubin, an abundant pigment that causes jaundice, has long lacked any clear physiologic role. It arises from enzymatic reduction by biliverdin reductase of biliverdin, a product of heme oxygenase activity. Bilirubin is a potent antioxidant that we show can protect cells from a 10,000-fold excess...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138570/ https://ncbi.nlm.nih.gov/pubmed/12456881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252626999 |
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