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K-cell-mediated cytotoxicity induced with rat monoclonal antibodies. I. Antibodies of various isotypes differ in their ability to induce cytotoxicity mediated by rat and human effectors.

Among the rat antibodies tested in this study, monoclonals of IgG2a isotype were the best, IgG1 and IgG2b being also effective, for induction of K-cell-mediated cytotoxicity of relevant nucleated target cells by rat effectors (Nude spleen cells). The single rat monoclonal IgE tested was also active....

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Detalhes bibliográficos
Main Authors: Chassoux, D M, Linares-Cruz, L G, Bazin, H, Stanislawski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385574/
https://ncbi.nlm.nih.gov/pubmed/3220507
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