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Antibodies to IFN-gamma prevent immunologically mediated intestinal damage in murine graft-versus-host reaction.

We have tested the hypothesis that interferon-gamma (IFN-gamma) plays a role in the enteropathy of graft-versus-host reaction (GVHR) by treating host mice with a monoclonal antibody directed at this mediator. Two models of GVHR were examined. In the mild proliferative GVHR, which occurs in adult uni...

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Detalles Bibliográficos
Autor Principal: Mowat, A M
Formato: Artigo
Idioma:Inglês
Publicado: 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385499/
https://ncbi.nlm.nih.gov/pubmed/2509325
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