Differential responsiveness of human B lymphocytes to phorbol ester and calcium ionophore based on their state of activation.

For tonsil B cells of a particular high density (below 65% Percoll), both phorbol myristate acetate (PMA) (5 ng/ml) and calcium ionophore A23187 (500 nM) were required to induce RNA synthesis, significant DNA synthesis also occurring in the presence of 12,000 MW B-cell growth factor (BCGF). In contr...

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Autors principals: Inglés, J, Engel, P, De La Calle, O, Gallart, T
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385353/
https://ncbi.nlm.nih.gov/pubmed/2503437
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