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Synergistic effect of blending IgG1 and IgG3 monoclonal anti-D in promoting the metabolic response of monocytes to sensitized red cells.

Monoclonal antibodies specific for the Rh antigen D were used to sensitize red cells for use in a series of cellular assays. IgG3 anti-D was more efficient than IgG1 anti-D in promoting the attachment and lysis of red cells by human monocytes. In contrast, IgG1 anti-D was more efficient at mediating...

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Detalhes bibliográficos
Main Authors: Hadley, A G, Kumpel, B M
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385332/
https://ncbi.nlm.nih.gov/pubmed/2504663
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