Abnormal rearrangements of T-cell receptor genes occur in long-term cultured bone marrow cells of lpr/lpr mice.

To search the abnormality in prethymic T-cell precursors in lpr/lpr(lpr) mice, rearrangement and expression of T-cell receptor (TcR) genes were investigated in long-term cultured bone marrow (LTBM) cells of lpr mice, in which the developmental steps of T-cell precursors may be better synchronized th...

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Main Authors: Ohga, S, Yoshikai, Y, Matsumoto, K, Kishihara, K, Matsuzaki, G, Nomoto, K
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385330/
https://ncbi.nlm.nih.gov/pubmed/2548951
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