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Activation and proliferation signals in mouse B cells. IX. Protein kinase C activators synergize with non-mitogenic anti-immunoglobulin antibodies to drive B cells into G1.

Intact (IgG) rabbit anti-Ig antibodies, unlike F(ab')2 fragments, do not induce DNA synthesis in murine B cells. The F(ab')2 antibodies induce prolonged breakdown of phosphatidylinositol bisphosphate, and hence activation of protein kinase C (PKC) in B cells, whilst the non-mitogenic antib...

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Detalhes bibliográficos
Main Authors: Bijsterbosch, M K, McLaughlin, J B, Holman, M, Klaus, G G
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385202/
https://ncbi.nlm.nih.gov/pubmed/3260215
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