Modulation of leukotriene release from human polymorphonuclear leucocytes by PMA and arachidonic acid.

Stimulation of human neutrophils (PMN) with Ca ionophore A23187, opsonized zymosan and formyl-L-methionyl-L-leucyl-phenylalanine (FMLP) led to a time- and dose-dependent release of LTB4, 20-OH-LTB4, 20-COOH-LTB4, 6-trans-LTB4, 12-epi-6-trans LTB4 and LTC4, as detected by reverse-phase HPLC. Preincub...

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Bibliographic Details
Main Authors: Raulf, M, König, W
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385185/
https://ncbi.nlm.nih.gov/pubmed/2838420
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