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Soluble malarial antigens are toxic and induce the production of tumour necrosis factor in vivo.

Heat-stable soluble products of rodent malarial parasites induce activated peritoneal macrophages to secrete tumour necrosis factor (TNF) in vitro. Since heat-stable parasite antigens are known to be present in the circulation of patients with malaria and it has been suggested that much of the patho...

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Bibliographic Details
Main Authors: Bate, C A, Taverne, J, Playfair, J H
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385164/
https://ncbi.nlm.nih.gov/pubmed/2654012
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