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Characterization of the spontaneous autoimmune (anti-erythrocyte) response in NZB mice using a pathogenic monoclonal autoantibody and its anti-idiotype.

A monoclonal anti-mouse RBC antibody (G-8) has been prepared that appears to represent a pathogenic autoantibody related to those that arise spontaneously in aging NZB mice and which cause autoimmune haemolytic disease (AIHD). When G-8-producing hybridoma cells were grown as tumours in BALB/c mice,...

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Bibliographische Detailangaben
Hauptverfasser: Caulfield, M J, Stanko, D, Calkins, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385093/
https://ncbi.nlm.nih.gov/pubmed/2925223
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