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Anti-viral immunity induced by recombinant nucleoprotein of influenza A virus. III. Delivery of recombinant nucleoprotein to the immune system using attenuated Salmonella typhimurium as a live carrier.

A plasmid encoding the influenza nucleoprotein gene from A/NT/60/68 virus was transduced into the attenuated Salmonella typhimurium aroA- strain SL3261. The bacterial vector expressing the viral gene product was able to induce both humoral and cell-mediated immune responses to the nucleoprotein anti...

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Bibliografiske detaljer
Main Authors: Tite, J P, Gao, X M, Hughes-Jenkins, C M, Lipscombe, M, O'Callaghan, D, Dougan, G, Liew, F Y
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384261/
https://ncbi.nlm.nih.gov/pubmed/2168340
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