Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.

Human cells are relatively resistant to lysis by the homologous complement system. Here we describe the mechanism of action of a recently discovered and widely distributed 18,000-20,000 molecular weight (MW) membrane glycoprotein (CD59), which appears to act as a major protective element against com...

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Main Authors: Meri, S, Morgan, B P, Davies, A, Daniels, R H, Olavesen, M G, Waldmann, H, Lachmann, P J
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384213/
https://ncbi.nlm.nih.gov/pubmed/1698710
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