Cleavage of human complement component C5 by cysteine proteinases from Porphyromonas (Bacteroides) gingivalis. Prior oxidation of C5 augments proteinase digestion of C5.

Since severe periodontitis is characterized by an acute inflammatory response with cellular infiltration and microbial overgrowth, plasma proteins could be exposed to both proteinases and oxidants released from the granulocytes, as well as to proteinases from the microorganisms. When human complemen...

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Dettagli Bibliografici
Autori principali: Discipio, R G, Daffern, P J, Kawahara, M, Pike, R, Travis, J, Hugli, T E, Potempa, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384148/
https://ncbi.nlm.nih.gov/pubmed/8675224
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