Chlorpromazine inhibits tumour necrosis factor synthesis and cytotoxicity in vitro.

Chlorpromazine (CPZ) has been previously shown to protect against endotoxin [lipopolysaccharide (LPS)] lethality and inhibit the release of tumour necrosis factor in vivo. We investigated at the cellular level whether this was due to direct inhibition of tumour necrosis factor-alpha (TNF-alpha) synt...

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Main Authors: Zinetti, M, Galli, G, Demitri, M T, Fantuzzi, G, Minto, M, Ghezzi, P, Alzani, R, Cozzi, E, Fratelli, M
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383945/
https://ncbi.nlm.nih.gov/pubmed/8550079
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