Methodologic quality and genotyping reproducibility in studies of tumor necrosis factor −308 G→A single nucleotide polymorphism and bacterial sepsis: Implications for studies of complex traits

OBJECTIVE: Studies of genetic associations with common diseases, such as between cytokine gene polymorphisms and severe bacterial sepsis, have reached conflicting conclusions. Failure to follow methodologic standards may have contributed to discordant findings. The −308 G→A transition in the tumor n...

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Autores principales: Peters, Dixie L., Barber, Robert C., Flood, Elizabeth M., Garner, Harold R., O’Keefe, Grant E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383771/
https://ncbi.nlm.nih.gov/pubmed/12794406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.CCM.0000065190.24116.A4
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