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TLR4 and TNF-α polymorphisms are associated with an increased risk for severe sepsis following burn injury

Context: Sepsis, organ failure, and shock remain common among patients with moderate to severe burn injuries. The inability of clinical factors to identify at-risk patients suggests that genetic variation may influence the risk for serious infection and the outcome from severe injury. Objective: Res...

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Autores principales: Barber, R, Aragaki, C, Rivera-Chavez, F, Purdue, G, Hunt, J, Horton, J
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383768/
https://ncbi.nlm.nih.gov/pubmed/15520404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2004.021600
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