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A Bioinformatics-Based Strategy Identifies c-Myc and Cdc25A as Candidates for the Apmt Mammary Tumor Latency Modifiers

The epistatically interacting modifier loci (Apmt1 and Apmt2) accelerate the polyoma Middle-T (PyVT)-induced mammary tumor. To identify potential candidate genes loci, a combined bioinformatics and genomics strategy was used. On the basis of the assumption that the loci were functioning in the same...

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Détails bibliographiques
Auteurs principaux: Cozma, Diana, Lukes, Luanne, Rouse, Jessica, Qiu, Ting Hu, Liu, Edison T., Hunter, Kent W.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383737/
https://ncbi.nlm.nih.gov/pubmed/12045150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.210502
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