The structural roles of a conserved small hydrophobic core in the active site and an ionic bridge in domain I of Delta class glutathione S-transferase

GSTs (glutathione S-transferases; E.C.2.5.1.18) are a supergene family of dimeric multifunctional enzymes that have a major role in detoxification pathways. Using a GST from the mosquito Anopheles dirus (adGSTD4-4), we have characterized the enzymatic and physical properties of Leu-6, Thr-31, Leu-33...

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Main Authors: Vararattanavech, Ardcharaporn, Prommeenate, Peerada, Ketterman, Albert J.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2005
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383667/
https://ncbi.nlm.nih.gov/pubmed/16153184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050555
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