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B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

The protein phosphatase 2A (PP2A) acts on several kinases in the extracellular signal-regulated kinase (ERK) signaling pathway but whether a specific holoenzyme dephosphorylates ERK and whether this activity is controlled during mitogenic stimulation is unknown. By using both RNA interference and ov...

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Detalhes bibliográficos
Main Authors: Letourneux, Claire, Rocher, Géraldine, Porteu, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383561/
https://ncbi.nlm.nih.gov/pubmed/16456541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600980
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