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Transcription regulation from a TATA and INR-less promoter: spatial segregation of promoter function

The mode of regulation of class II genes that lack the known core promoter elements is presently unclear. Here, we studied one such example, the murine CD80 gene. An unusual mechanism was revealed wherein the pre-initiation complex (PIC) first assembled on an upstream, NF-κB enhancer element. Notabl...

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Detalhes bibliográficos
Main Authors: George, Anuja A, Sharma, Manish, Singh, Badri N, Sahoo, Naresh C, Rao, Kanury VS
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383549/
https://ncbi.nlm.nih.gov/pubmed/16437157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600966
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