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Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways

The yeast Doa10 ubiquitin (Ub) ligase resides in the endoplasmic reticulum (ER)/nuclear envelope (NE), where it functions in ER-associated degradation (ERAD). Doa10 substrates include non-ER proteins such as the transcription factor Matα2. Here, we expand the range of Doa10 substrates to include a d...

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Bibliografske podrobnosti
Main Authors: Ravid, Tommer, Kreft, Stefan G, Hochstrasser, Mark
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383530/
https://ncbi.nlm.nih.gov/pubmed/16437165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600946
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