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Initiation of DNA repair mediated by a stalled RNA polymerase IIO

The transcription-coupled repair (TCR) pathway preferentially repairs DNA damage located in the transcribed strand of an active gene. To gain insight into the coupling mechanism between transcription and repair, we have set up an in vitro system in which we isolate an elongating RNA pol IIO, which i...

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Main Authors: Lainé, Jean-Philippe, Egly, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383516/
https://ncbi.nlm.nih.gov/pubmed/16407975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600933
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