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A role for the Rab6A′ GTPase in the inactivation of the Mad2-spindle checkpoint

The two isoforms of the Rab6 GTPase, Rab6A and Rab6A′, regulate a retrograde transport route connecting early endosomes and the endoplasmic reticulum via the Golgi complex in interphasic cells. Here we report that when Rab6A′ function is altered cells are unable to progress normally through mitosis....

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Detalhes bibliográficos
Main Authors: Miserey-Lenkei, Stéphanie, Couëdel-Courteille, Anne, Del Nery, Elaine, Bardin, Sabine, Piel, Matthieu, Racine, Victor, Sibarita, Jean-Baptiste, Perez, Franck, Bornens, Michel, Goud, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383512/
https://ncbi.nlm.nih.gov/pubmed/16395330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600929
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