Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors

The Maf-family transcription factor Nrl is a key regulator of photoreceptor differentiation in mammals. Ablation of the Nrl gene in mice leads to functional cones at the expense of rods. We show that a 2.5-kb Nrl promoter segment directs the expression of enhanced GFP specifically to rod photorecept...

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Detalhes bibliográficos
Main Authors: Akimoto, Masayuki, Cheng, Hong, Zhu, Dongxiao, Brzezinski, Joseph A., Khanna, Ritu, Filippova, Elena, Oh, Edwin C. T., Jing, Yuezhou, Linares, Jose-Luis, Brooks, Matthew, Zareparsi, Sepideh, Mears, Alan J., Hero, Alfred, Glaser, Tom, Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383502/
https://ncbi.nlm.nih.gov/pubmed/16505381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508214103
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