RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma.

BACKGROUND: CYP2E1, the coding gene for the ethanol inducible cytochrome P4502E1, is polymorphic at the RsaI restriction site in the 5' flanking region. The mutant allele c2 has a higher transcriptional activity than the wild-type gene c1. P4502E1 catalyses the activation of several environment...

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Autores principales: Ladero, J M, Agúndez, J A, Rodríguez-Lescure, A, Diaz-Rubio, M, Benítez, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383320/
https://ncbi.nlm.nih.gov/pubmed/8977352
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