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High pH reduces DNA damage caused by bile from patients with familial adenomatous polyposis: antacids may attenuate duodenal polyposis.

Patients with familial adenomatous polyposis (FAP) develop periampullary duodenal tumours, suggesting that bile contributes to their formation. The hypothesis that bile contains carcinogens has been tested by looking for DNA adducts (markers of carcinogen exposure) in the duodenum of patients with o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scates, D K, Venitt, S, Phillips, R K, Spigelman, A D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382633/
https://ncbi.nlm.nih.gov/pubmed/7615284
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