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Activation of the lutropin/choriogonadotropin receptor (LHR) in MA-10 cells leads to the tyrosine phosphorylation of the focal adhesion kinase (FAK) by a pathway that involves Src family kinases

We show that activation of the endogenous or recombinant LHR in mouse Leydig tumor cells (MA-10 cells) leads to the tyrosine phosphorylation of the focal adhesion kinase (FAK) and one of its substrates (paxillin). Using specific antibodies to the five tyrosine residues of FAK that become phosphoryla...

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Detalhes bibliográficos
Main Authors: Mizutani, Tetsuya, Shiraishi, Koji, Welsh, Toni, Ascoli, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382007/
https://ncbi.nlm.nih.gov/pubmed/16293639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2005-0277
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