Metabolism of 2',3'-dideoxyinosine (ddI) in human blood.

1. 2',3'-Dideoxyinosine (ddI) has potent activity against human immunodeficiency virus (HIV). It is converted within target cells to its active form dideoxyadenosine triphosphate(ddA-TP). 2. In addition to the intracellular formation of ddA-TP, ddI can be broken down to hypoxanthine, by pu...

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Dades bibliogràfiques
Autors principals: Back, D J, Ormesher, S, Tjia, J F, Macleod, R
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1381283/
https://ncbi.nlm.nih.gov/pubmed/1576055
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