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Improved Power Offered by a Score Test for Linkage Disequilibrium Mapping of Quantitative-Trait Loci by Selective Genotyping

Selective genotyping is used to increase efficiency in genetic association studies of quantitative traits by genotyping only those individuals who deviate from the population mean. However, selection distorts the conditional distribution of the trait given genotype, and such data sets are usually an...

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Detalhes bibliográficos
Main Authors: Wallace, Chris, Chapman, Juliet M., Clayton, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380292/
https://ncbi.nlm.nih.gov/pubmed/16465623
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