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A Testing Framework for Identifying Susceptibility Genes in the Presence of Epistasis

An efficient testing strategy called the “focused interaction testing framework” (FITF) was developed to identify susceptibility genes involved in epistatic interactions for case-control studies of candidate genes. In the FITF approach, likelihood-ratio tests are performed in stages that increase in...

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Detalhes bibliográficos
Main Authors: Millstein, Joshua, Conti, David V., Gilliland, Frank D., Gauderman, W. James
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380213/
https://ncbi.nlm.nih.gov/pubmed/16385446
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