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Lowering of theophylline clearance by isoniazid in slow and rapid acetylators.

The effect of isoniazid (INH) pretreatment (400 mg daily for 2 weeks) on the elimination kinetics of theophylline (given intravenously as aminophylline equivalent to 151.2 mg theophylline) was investigated in 13 healthy male non-smokers. Amongst the 13 subjects studied, seven were rapid and six were...

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Detalhes bibliográficos
Main Authors: Samigun, Mulyono, Santoso, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380157/
https://ncbi.nlm.nih.gov/pubmed/2350534
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