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Influence of acetylator status on the haemodynamic effects and pharmacokinetics of cadralazine in healthy subjects.

1. Cadralazine is a new antihypertensive agent which causes peripheral vasodilation, probably mediated by a hydrazinopyridazine metabolite. 2. The possible influence of acetylator status on the pharmacokinetics and haemodynamics of the drug was studied in six fast and six slow acetylators over a per...

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Autores principales: Brunel, P, Lecaillon, J B, Guyene, T T, Imhof, P, Ménard, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380148/
https://ncbi.nlm.nih.gov/pubmed/2190629
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