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Influence of acetylator status on the haemodynamic effects and pharmacokinetics of cadralazine in healthy subjects.
1. Cadralazine is a new antihypertensive agent which causes peripheral vasodilation, probably mediated by a hydrazinopyridazine metabolite. 2. The possible influence of acetylator status on the pharmacokinetics and haemodynamics of the drug was studied in six fast and six slow acetylators over a per...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
1990
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1380148/ https://ncbi.nlm.nih.gov/pubmed/2190629 |
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