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A dose-effect study of the in vivo inhibitory effect of quinidine on sparteine oxidation in man.

1. Twelve healthy extensive metabolisers of sparteine were sparteine tested daily for 6 days (19.00 h to 07.00 h). A small but statistically significant rise in sparteine metabolic ratio (MR) was observed. 2. Following 100 mg quinidine sulphate given to four of the subjects at 16.00 h, sparteine tes...

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Dettagli Bibliografici
Autori principali: Nielsen, M D, Brøsen, K, Gram, L F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380129/
https://ncbi.nlm.nih.gov/pubmed/2310654
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