Pharmacological investigations of a new renin inhibitor in normal sodium-unrestricted volunteers.

1. CGP 38 560 A, a low-molecular-weight, non-peptidic renin inhibitor, was well tolerated upon intravenous and oral administration to recumbent healthy volunteers on an unrestricted-sodium diet. 2. After intravenous infusion over 30 min at a rate of 100 ml h-1, doses of 50, 125 and 250 micrograms kg...

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Main Authors: de Gasparo, M, Cumin, F, Nussberger, J, Guyenne, T T, Wood, J M, Menard, J
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379924/
https://ncbi.nlm.nih.gov/pubmed/2667598
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