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Co-administration of ciprofloxacin and cyclosporin: lack of evidence for a pharmacokinetic interaction.

Ciprofloxacin is widely reported to lower theophylline clearance in patients. Since cyclosporin and theophylline are metabolized by cytochrome P-450 enzymes in the human liver, we investigated whether ciprofloxacin could alter the pharmacokinetics of cyclosporin in healthy volunteers. There was no s...

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Detalhes bibliográficos
Main Authors: Tan, K K, Trull, A K, Shawket, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379903/
https://ncbi.nlm.nih.gov/pubmed/2775624
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