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Pharmacokinetic and pharmacodynamic interactions between the ACE inhibitor cilazapril and β-adrenoceptor antagonist propranolol in healthy subjects and in hypertensive patients

1 Six healthy subjects received cilazapril (2.5 mg once daily), propranolol (120 mg once daily), the combination of both and placebo for a period of 1 week each (wash-out phase 1 week). 2 Propranolol and cilazapril reduced systolic and diastolic blood pressure (BP) by 7 mm Hg at peak when compared w...

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Autors principals: Belz, G. G., Essig, J., Erb, K., Breithaupt, K., Hoogkamer, J. F. W., Kneer, J., Kleinbloesem, C. H.
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379764/
https://ncbi.nlm.nih.gov/pubmed/2527545
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