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The pharmacokinetics and angiotensin converting enzyme inhibition dynamics of cilazapril in essential hypertension

1 In a double-blind, placebo controlled, crossover study 12 patients with essential hypertension received single doses of 5, 10 and 20 mg of cilazapril. 2 Peak plasma levels of cilazaprilat and the 24 h areas under curve were directly proportional to dose. 3 The elimination half-life during the firs...

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Detalhes bibliográficos
Main Authors: Meredith, P. A., Elliott, H. L., Reid, J. L., Francis, R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379756/
https://ncbi.nlm.nih.gov/pubmed/2548553
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