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Rate-controlled rectal absorption enhancement of cefoxitin by co-administration of sodium salicylate or sodium octanoate in healthy volunteers.

1. The effects of sodium octanoate and sodium salicylate on the rectal absorption of cefoxitin were investigated in healthy volunteers. Drug solutions were given either as a bolus or as a zero-order infusion. 2. On rectal infusion sodium octanoate and sodium salicylate both enhanced mean cefoxitin b...

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Bibliographische Detailangaben
Hauptverfasser: Van Hoogdalem, E J, Wackwitz, A T, De Boer, A G, Cohen, A F, Breimer, D D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379707/
https://ncbi.nlm.nih.gov/pubmed/2706190
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