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Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-d-aspartate (NMDA) receptor coagonist d-serine

High levels of d-serine occur in the brain, challenging the notion that d-amino acids would not be present or play a role in mammals. d-serine levels in the brain are even higher than many l-amino acids, such as asparagine, valine, isoleucine, and tryptophan, among others. d-serine is synthesized by...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: de Miranda, Joari, Panizzutti, Rogerio, Foltyn, Veronika N., Wolosker, Herman
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12393813/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222421299
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