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Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

RNA interference (RNAi) using double-stranded RNA has been used for the systematic analysis of gene function in invertebrate organisms. Here we have explored the use of short interfering RNA (siRNA) to knock down gene expression during the development of mammalian postimplantation embryos. The devel...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Calegari, Federico, Haubensak, Wulf, Yang, Dun, Huttner, Wieland B., Buchholz, Frank
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192559699
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