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RB activation defect in tumor cell lines

Activation of the retinoblastoma (RB) protein through dephosphorylation arises in cells upon exit from M phase and in response to environmental stresses, including DNA damage. We provide here for the first time evidence that these responses are co-ordinately affected in a subset of tumor derived cel...

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Bibliografiske detaljer
Main Authors: Broceño, Cristina, Wilkie, Scott, Mittnacht, Sibylle
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137861/
https://ncbi.nlm.nih.gov/pubmed/12379745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212519499
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